Promethazine codeine syrup - An Overview
Promethazine codeine syrup - An Overview
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Promethazine HCl and Codeine Phosphate Oral Option needs to be made use of with caution in people with extreme impairment of renal functionality, and clients needs to be monitored carefully for respiratory depression, sedation, and hypotension.
Normally, dose range for an elderly individual must be cautious, generally starting off for the reduced conclude on the dosing assortment, reflecting the bigger frequency of reduced hepatic, renal or cardiac function, and of concomitant ailment or other drug therapy.
Promethazine hydrochloride happens as being a white to faint yellow, virtually odorless, crystalline powder which little by little oxidizes and turns blue on prolonged exposure to air.
Acute or extreme bronchial bronchial asthma within an unmonitored environment or in absence of resuscitative devices. (4)
When utilized for an extended time, this medication may not work also and should involve diverse dosing. Talk to your doctor if this medication stops Doing the job nicely.
Speak with your care group about using this medication in small children. This medication will not be to be used in small children younger than 12 yrs of age. Don't give this medication to a toddler more youthful than eighteen many years of age just after surgical procedures to remove the tonsils and/or adenoids.
Codeine Codeine is undoubtedly an opioid agonist relatively selective with the mu-opioid receptor, but which has a much weaker affinity than morphine. The analgesic and antitussive properties of codeine are speculated to originate from its conversion to morphine.
When the response to an opioid antagonist is suboptimal or only brief in nature, administer extra antagonist as directed from the product’s prescribing facts. The respiratory depressant outcomes of promethazine usually are not reversed by opioid antagonists, for instance naloxone.
Bluish lips or pores and skin chills clay-colored stools cold sweats confusion cough dim urine decrease in the frequency of urination reduce inside the urine quantity diarrhea complicated or troubled breathing issues in passing urine (dribbling) dizziness dizziness, faintness, or lightheadedness when having up from lying or sitting position quick, pounding, or irregular heartbeat or pulse experience of heat fever headache substantial fever hives or welts, itching, or rash elevated perspiring irregular, quickly or gradual, or shallow breathing significant, hive-like swelling over the facial area, eyelids, lips, tongue, throat, fingers, legs, ft, or sex organs lack of urge for food loss of bladder Regulate nausea noisy respiration not breathing agonizing urination pale or blue lips, fingernails, or pores and skin rectal bleeding redness with the experience, neck, arms, and occasionally, higher upper body redness on the skin observing, hearing, or experience matters that aren't there seizures severe muscle stiffness shakiness during the legs, arms, or palms belly agony perspiring tightness while in the chest tiredness trembling or shaking from the palms or feet uncomfortable breath odor uncommon tiredness or weak point unusually pale skin vomiting of blood yellow eyes or skin Get crisis assist right away if any of the next indications of overdose occur:
If this SPL contains inactivated NDCs stated via the FDA initiated compliance action, they will be specified as such.
Promethazine hydrochloride was not mutagenic during the in vitro bacterial reverse mutation assay or clastogenic within the in vitro Chinese hamster ovary (CHO) mobile chromosomal aberration assay.
Respiration difficulties (respiratory depression)that may result in Demise and opioid withdrawal can take place if You begin having or end using other medicines although having Promethazine Hydrochloride and Codeine Phosphate Oral Solution, which include:
Ahead of applying this medication, Females of childbearing age really should speak with their doctor(s) in regards to the challenges and Added benefits. Notify your doctor Should you be Expecting or Imagine you could be Expecting. All through pregnancy, this medication just isn't proposed. It might somewhat improve the hazard of delivery defects if made use of throughout the 1st two months of pregnancy. Also, making use of it for some time or in high doses near the expected supply date Promethazine codeine syrup might damage the unborn newborn.
To lower the risk of dizziness and lightheadedness, get up gradually when increasing from a sitting down or lying place.